Identifying Frail-Related Biomarkers among Community-Dwelling Older Adults in Japan: A Research Example from the Japanese Gerontological Evaluation Study

نویسندگان

  • N Cable
  • A Hiyoshi
  • N Kondo
  • J Aida
  • H Sjöqvist
  • K Kondo
چکیده

We examined correlating clinical biomarkers for the physical aspect of frailty among community-dwelling older adults in Japan, using Japanese Gerontological Evaluation Study (JAGES). We used information from the JAGES participants (N = 3,128) who also participated in the community health screening in 2010. We grouped participants' response to the Study of Osteoporotic Fracture (SOF) Frailty Index into robust (=0), intermediate frail (=1), and frail (=2+) ones to indicate physical aspect of frailty. Independent of sex and age, results from multinomial logistic regression showed above normal albumin and below normal HDL and haemoglobin levels were positively associated with intermediate frail (RRR = 1.99, 95% CI = 1.22-3.23; RRR = 1.36, 95% CI = 1.33-1.39; RRR = 1.36, 95% CI = 1.23-1.51, resp.) and frail cases (RRR = 2.27, 95% CI = 1.91-2.70; RRR = 1.59, 95% CI = 1.51-1.68; RRR = 1.40, 95% CI = 1.28-1.52, resp.). Limited to women, above normal Hb1Ac level was similarly associated with intermediate frail and frail cases (RRR = 1.18, 95% CI = 1.02, 1.38; RRR = 2.56, 95% CI = 2.23-2.95, resp.). Use of relevant clinical biomarkers can help in assessment of older adults' physical aspect of frailty.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Nutritional status and dysphagia risk among community-dwelling frail older adults.

OBJECTIVES Although the presence of dysphagia is a key determinant of nutritional status among older adults, few studies have focused on the association between malnutrition and dysphagia risk in community-dwelling frail older adults. This study estimated the prevalence of malnutrition and quantified the association between malnutrition and dysphagia risk among community-dwelling older Japanese...

متن کامل

Evaluation of Quality of Life and its Related Factors in Elderly in Mashhad in 1396

Objectives As Iran is one of the countries in the world which its population moves toward aging rapidly, it is essential to consider older adults' needs and concerns, which might have an impact on their health-related quality of life. Quality of life is a multi-dimensional concept that has physical, mental, and social components. The present study has been conducted to determine the correlation...

متن کامل

Impact of physical frailty on disability in community-dwelling older adults: a prospective cohort study

OBJECTIVE To examine the relationship between physical frailty and risk of disability, and to identify the component(s) of frailty with the most impact on disability in community-dwelling older adults. DESIGN Prospective cohort study. SETTING A Japanese community. PARTICIPANTS 4341 older adults aged ≥65 living in the community participated in a baseline assessment from 2011 to 2012 and we...

متن کامل

Examining the Protective Role of Spiritual-wellbeing on Fear of COVID-19 among Community-dwelling Older Adults in 2021

Introduction: Fear has been one of the most frequent emotions associated with the COVID-19 pandemic. Older people are at risk for severe COVID-19 infection. Spiritual-wellbeing can play an important role in patients' coping and adaptation to stressful conditions related to disorders. Therefore, the present study was aimed to determine the predictive role of spiritual-wellbeing on reducing the f...

متن کامل

Prevalence of Cognitive Impairment in Community-Dwelling Older Adults

Introduction: Mild cognitive impairment can be considered as an intermediate clinical state between normal cognitive aging and mild dementia. Elderly people with this impairment represent an at-risk group for the development of dementia. The aim of this study was to investigate the prevalence of cognitive impairment in community-dwelling older adults by Mini-Mental State Examination (MMSE) and ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 2018  شماره 

صفحات  -

تاریخ انتشار 2018